In a cavernous production facility at AAI Unmanned Aircraft Systems in Hunt Valley, workers assemble remote-control planes that help U.S. forces identify enemy targets.
At the Johns Hopkins University Applied Physics Laboratory in Laurel, researchers work to make drones behave like insects, communicating among themselves as they perform a task together.
And at Naval Air Station Patuxent River in Southern Maryland, the Navy is testing a new unmanned jet flier designed to take off from and land on aircraft carriers.
Manufacturers such as AAI, Lockheed Martin and others, research at Johns Hopkins, the University of Maryland and elsewhere, and testing at the Patuxent station and Aberdeen Proving Ground have combined to make the state a center of a burgeoning global industry.
"The market is going to grow exponentially," said Mike Hayes, the retired Marine Corps general who heads the state's office of military and federal affairs. "And then, as the [Federal Aviation Administration] comes to grips with airspace issues and safety associated with unmanned systems, the potential for growth is even more dramatic.
"Within Maryland, because of a combination of our universities, our federal installations and then some of the private-sector folks that are already involved, we think we're very well-positioned to participate."
The industry faces challenges. With the United States out of Iraq and drawing forces down in Afghanistan, President Barack Obama has ordered the Pentagon to slow the growth of future spending. Congress is stalemated over a budget deal needed to forestall additional cuts.
The growing reliance on unmanned aircraft, meanwhile, has sparked controversy. Critics have said that using weaponized drones to kill individuals overseas is akin to assassination, and have protested the attendant civilian casualties.
Civil libertarians have expressed concern about the introduction of surveillance aircraft to domestic airspace, even as companies promote their value for such uses as watching borders and monitoring traffic.
And there remain concerns about the safe integration of manned and unmanned air traffic in the skies over the United States — concerns stoked in part by incidents such as the June crash of an RQ-4A Global Hawk on Maryland's Eastern Shore.
Still, as an expanding roster of countries use unmanned aircraft to fly a widening array of missions, industry officials and analysts expect spending on drones to grow.
The Teal Group, a Virginia firm that tracks the aerospace and defense industries, estimates the global market for unmanned aerial vehicles will nearly double over the next decade to $11.4 billion.
"What we see is some immediate pressure in the U.S. on [unmanned aerial vehicle] spending," said Philip Finnegan, director of corporate analysis for the Teal Group. "But over the next few years, there will be pressure upwards because of the focus on the next generation of systems."
International spending, meanwhile, will more than triple over the next 10 years, Finnegan says.
State officials see gains for Maryland.
Hayes' office counts at least two dozen businesses in the state that work on unmanned aircraft. They range from small, specialty firms that produce components to aircraft manufacturers such as AAI and Lockheed Martin, maker of the K-MAX cargo helicopter and the Desert Hawk III surveillance plane, among others.
"We think we are very well-positioned to be at the forefront of wherever this path leads us," Hayes said.
Maryland institutions are helping to blaze the trail. In June, the Hopkins Applied Physics Laboratory demonstrated with Boeing that an operator on the ground with limited training, and using only a laptop and a military radio, can command a swarm of unmanned vehicles.
The swarm technology developed by the laboratory enables drones to communicate and act in concert to complete tasks more quickly and efficiently.